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[2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone

Product Name [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone
Product Code A00007530
Chemical name [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone
Synonyms 1-[2-[(2-Amino-4-chlorophenyl)amino]benzoyl]-4-methylpiperazine; Clozapine EP Impurity D; Clozapine EP Impurity D
Impurity Clozapine EP Impurity D
CAS Number 65514-71-8
Alternate CAS #
Molecular form C₁₈H₂₁ClN₄O
Appearance Pink to Light red Solid
Melting Point >103°C (dec.)
Mol. Weight 344.84
Storage Refrigerator
Solubility DMSO (Slightly), Methanol (Slightly)
Stability
Category Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point
Applications [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone (Clozapine EP Impurity D) is used in the synthesis of substituted dibenzodiazepines. Also an impurity in the synthesis of Clozepine (C587500), an antipsychotic.
Dangerous Goods Info
References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)
Extra Notes
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[2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone
Product Packings
10mg
100mg
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